It is crucial to tell your medical professional should you develop into Expecting. Your health care provider may want you to affix a pregnancy registry for patients having this medicine.
Allergic reactions such as rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome may almost never be induced by an immunological response to modafinil or its metabolites.
For sentralt godkjente legemidler ligger alle styrker og legemiddelformer etter hverandre i samme dokument.
With that mind, what will we presently understand about modafinil’s likely for setting up physiological tolerance and drug-dependence?
Contraindicated (two)modafinil will enhance the amount or impact of mavacamten by influencing hepatic enzyme CYP2C19 metabolism. Contraindicated. Powerful or moderate CYP2C19 inhibitors may boost mavacamten systemic publicity, resulting in coronary heart failure on account of systolic dysfunction.
Indicated to further improve wakefulness in Older people with too much sleepiness associated with shift work problem (SWD)
According to some preliminary reports, modafinil may well act by partially inhibiting the dopamine transporter
This medication might result in you to possess a serious sort of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires speedy health care awareness.
cannabidiol will raise the level or result of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Intently. Look at lowering the dose of delicate CYP2C19 substrates, as clinically appropriate, when coadministered with cannabidiol.
Istradefylline forty mg/working day enhanced peak concentrations and AUC of CYP3A4 substrates in clinical trials. This result was not noticed with istradefylline twenty mg/working day. Look at dose reduction of delicate CYP3A4 substrates.
Other Unintended effects not stated could also arise in certain individuals. In case you recognize another consequences, Examine along with your Health care Qualified.
Behandling skal initieres av eller less than tilsyn av lege med tilstrekkelig erfaring i diagnostisering og behandling av narkolepsi.
Tilstand som skyldes inntak av giftige stoffer, slik som legemidler, rusmidler, kjemikalier eller stoffer som finnes naturlig i dyr og planter, i en slik mengde at det kan føre til alvorlig skade.
Discontinue interfering medications for at least five half-life before administration get more info of possibly the dosimetry or an iobenguane dose. Will not administer these prescription drugs until eventually at least seven days following Each and every iobenguane dose.